The abortion industry is panicking after one of its most beloved icons, U.S. Supreme Court Justice Ruth Bader Ginsburg, died Friday, leaving an open seat on the high court.

On Monday, Planned Parenthood sent out a desperate fundraising email to supporters, urging them to “rise up” and use “the power of defiance” to stop President Donald Trump from appointing another conservative justice to the Supreme Court.

“Some of Justice Ginsburg’s most powerful opinions were dissents. She used the power of defiance to fuel her life’s work — now it’s up to us to do the same,” wrote Kelley Robinson, executive director of the Planned Parenthood Action Fund. “This might be our last chance to protect not only Roe v. Wade, but protect freedom and justice for decades to come.”

Planned Parenthood warned abortion activists that the future of abortion on demand is at stake. Trump’s nominee likely will be someone who will uphold the rule of law and refuse to be swayed by left-wing judicial activism. Trump’s list of potential Supreme Court nominees includes conservative jurists who have a history of upholding pro-life legislation and following the rule of law rather than legislating from the bench.

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If the U.S. Senate confirms his choice, pro-life leaders hope that the court will restore rights and protections for babies in the womb.

And that is what Planned Parenthood, a billion-dollar abortion chain, fears. Using fighting words, its president, Alexis McGill Johnson, urged supporters to fiercely oppose Trump’s choice.

“Our opposition thinks the vacancy left by Justice Ginsburg’s death is a victory for them,” she wrote. “But they have us to contend with, and we’re smarter, fiercer and more strategic — because we’ve had to be.”

Robinson, who runs the abortion chain’s political arm, echoed the call to battle.

“We know exactly what we need to do to honor her legacy: fight with everything we’ve got to protect our reproductive freedom,” she wrote. “Because if we don’t, … access to reproductive health care as we know it may vanish.”

The abortion chain is pinning its hopes on Democrat presidential candidate Joe Biden, who promised to appoint judges who support Roe v. Wade. Planned Parenthood plans to spend at least $45 million to elect Biden and other pro-abortion Democrats this fall.

“Rising as one voice, unwilling to back down, we can keep this vacancy from getting filled before a new president is sworn in next year,” Robinson wrote.

For Planned Parenthood, its business aborting more than 340,000 unborn babies each year is at stake as well as the $500 million in taxpayer funding it receives every year. A number of abortion cases in the court system right now potentially could be heard by the Supreme Court next year.

Trump is reportedly looking at a female nominee to replace Ginsburg. Potential nominees include Judge Amy Coney Barrett of the U.S. Court of Appeals for the Seventh Circuit, Judge Barbara Lagoa of the U.S. Court of Appeals for the 11th Circuit, and Judge Allison Jones Rushing of the U.S. Court of Appeals for the 4th Circuit.

Senate Majority Leader Mitch McConnell said Trump’s nominee for the Supreme Court will receive a vote in the Senate.

Throughout her nearly three decades on the court, Ginsburg consistently ruled against rights and protections for unborn babies. She also made discriminatory statements that are reflective of the old eugenics thinking rooted in abortion activism.

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